Histological Features of Intracranial Germinomas Not Disappearing Immediately After Radiotherapy
نویسندگان
چکیده
منابع مشابه
Radiologic features of primary intracranial ectopic germinomas
RATIONALE Germinomas are sensitive to radiation therapy and chemotherapy; therefore, correct imaging diagnosis is crucial for them. However, the imaging findings of germinomas originating from off-midline regions displayed different patterns from those originating from midline areas. PATIENT CONCERNS The objective of this study is to describe the radiologic features of primary ectopic germino...
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In this report we present two patients with intracranial multiple midline tumours in the suprasellar region and pineal gland. We postulate that in a patient with multiple midline tumours and normal values of the tumour markers human chorionic gonadotropin and alpha-fetoprotein in serum and cerebrospinal fluid, the only possible diagnosis is a germinoma. In such a situation no histological confi...
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Intracranial germinomas are rare and account for <0.5% of primary intracranial tumors. In contrast to the gonadal germinomas, these do not show granulomatous response within the tumor. In rare cases, the granulomatous component may obscure the tumor proper and lead to diagnostic difficulties/dilemmas. We report a case of suprasellar germinoma in a 17-year-old boy which showed granulomatous resp...
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Intracranial germinomas are uncommon tumors. In the past, patients have traditionally been diagnosed with a trial of focal radiotherapy without biopsy. If the tumor was radiosensitive, it was presumed to be a germinoma. Because of the minimal morbidity and mortality associated with microsurgical techniques, almost all patients now have a histologic diagnosis and can be treated appropriately. Ra...
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ABSTRACTIntracranial tumours often require radiotherapeutic approaches that differ from other sites. Their specific requirements merit a specialized discussion. A brief review of radiotherapy techniques to treat intracranial tumours is presented with emphasis on the author’s own experience and work, where appropriate. A clinical introduction is presented first followed by a description of bot...
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ژورنال
عنوان ژورنال: Neurologia medico-chirurgica
سال: 2006
ISSN: 0470-8105,1349-8029
DOI: 10.2176/nmc.46.429